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Prospective Cohort for Early Detection of Liver Cancer

NCT05541601 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 3000

Last updated 2022-09-15

No results posted yet for this study

Summary

This study aims to recruit 3000 people with liver cirrhosis into a Prospective cohort for early detection of Liver cancer - the Pearl cohort. The study team believe that using a combination of novel tests may improve the detection of early Hepatocellular Carcinoma (HCC).

Conditions

Interventions

OTHER

Blood and Urine samples

The samples will be used to identify a range of tests (including genetic, protein and other biomarkers), which along with the clinical data will hopefully identify those most at risk of developing HCC, and to identify HCC at the earliest possible time points.

Sponsors & Collaborators

  • Cancer Research UK

    collaborator OTHER

  • Roche Diagnostic Ltd.

    collaborator INDUSTRY

  • OncImmune Ltd

    collaborator UNKNOWN

  • Perspectum

    collaborator INDUSTRY

  • University of Nottingham

    collaborator OTHER

  • Glasgow Caledonian University

    collaborator OTHER

  • University of Oxford

    lead OTHER

Principal Investigators

  • Ellie Barnes · University of Oxford

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-02-23
Primary Completion
2037-07-31
Completion
2037-07-31

Countries

  • United Kingdom

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05541601 on ClinicalTrials.gov