Baveno VI Criteria in Dynamic Monitoring of High-risk Varices in Compensated Cirrhotic Patients

Summary

Patients meet Baveno VI criteria (with a liver stiffness \<20kPa and with a platelet count \>150,000 are considered to have very low risk of having varices requiring treatment, but whether these patients can be followed up by repetition of this criteria lacks sufficient evidence. This study aimed to assess the value of Baveno VI criteria for following up and monitoring of varices needing treatment in patients with compensated cirrhosis.

Conditions

• Cirrhosis
• Varices
• Non-invasive Evaluation

Interventions

DIAGNOSTIC_TEST

Complete blood count

Complete blood count will be conducted at 12th month and 24th month from baseline.

DIAGNOSTIC_TEST

Transient elastrography

Transient elastrography, and endoscopy will be conducted at 12th month and 24th month from baseline.

DIAGNOSTIC_TEST

Endoscopy

Endoscopy will be conducted at 12th month and 24th month from baseline.

Sponsors & Collaborators

• Fifth Hospital of Shijiazhuang City

  collaborator OTHER

• The Sixth Hospital of Qingdao

  collaborator UNKNOWN

• The Sixth Hospital of Dalian

  collaborator UNKNOWN

• The Third People's Hospital of Taiyuan

  collaborator OTHER

• The Fourth People's Hospital of Qinghai Province

  collaborator OTHER

• Affiliated Hospital of Nanjing University of Chinese Medicine

  collaborator OTHER

• The Fifth People's Hospital of Wuxi Affiliated Hospital of Jiangnan University

  collaborator UNKNOWN

• Beilun Hospital of Chinese Medicine

  collaborator UNKNOWN

• Gansu Wuwei Tumor Hospital

  collaborator OTHER

• The Affiliated Hospital of Xuzhou Medical University

  collaborator OTHER

• First Affiliated Hospital of Fujian Medical University

  collaborator OTHER

• The Third People's Hospital of Linfen City

  collaborator UNKNOWN

• The First Affiliated Hospital of Xian Jiaotong University

  collaborator UNKNOWN

• The Third Affiliated Hospital of Hebei Medical University

  collaborator UNKNOWN

• The First Affiliated Hospital of Anhui Medical University

  collaborator OTHER

• Liuzhou Workers' Hospital

  collaborator OTHER_GOV

• The First People's Hospital of Taicang

  collaborator UNKNOWN

• Xinjiang Hospital of Chinese Medicine

  collaborator UNKNOWN

• Taizhou People's Hospital

  collaborator UNKNOWN

• Shenzhen Third People's Hospital

  collaborator OTHER

• Huashan Hospital

  lead OTHER

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-09-30

Primary Completion

2022-12-31

Completion

2023-12-31