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The Effects of NSAIDs on Bone Metabolism Following Exercise

NCT05512013 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2023-11-29

No results posted yet for this study

Summary

The purpose of this study is to determine the effects of a single dose of non-steroidal anti-inflammatory drugs on post-exercise markers of bone and muscle metabolism.

Conditions

  • Bone Resorption
  • Stress Fracture
  • Bone Injury

Interventions

DRUG

Ibuprofen 800 mg

Ibuprofen taken orally 2 hours prior to exercise

DRUG

Celecoxib 200mg

Celebrex taken orally 2 hours prior to exercise

DRUG

Flurbiprofen 100 mg

Flurbiprofen taken orally 2 hours prior to exercise

DRUG

Placebo

Inert placebo taken orally 2 hours prior to exercise

Sponsors & Collaborators

  • United States Army Research Institute of Environmental Medicine

    lead FED

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
42 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-02-15
Primary Completion
2023-04-01
Completion
2023-04-01
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05512013 on ClinicalTrials.gov