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Variability in Response to Non-steroidal Anti-inflammatory Drugs

NCT02502006 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2023-12-13

Study results available
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Summary

This research study will evaluate inter-individual variability in the response to the non-steroidal anti-inflammatory drugs (NSAIDs), celecoxib and naproxen, among healthy adults. It will also investigate what factors, like age, sex, or genetic background, cause this variability.

Conditions

  • Healthy

Interventions

DRUG

Celecoxib

DRUG

Naproxen

DRUG

Placebo

Sponsors & Collaborators

Principal Investigators

  • Garret A FitzGerald, MD · University of Pennsylvania, Institute for Translational Medicine and Therapeutics

  • Tilo Grosser, MD · University of Pennsylvania, Institute for Translational Medicine and Therapeutics

  • Katherine N Theken, PharmD, PhD · University of Pennsylvania, Institute for Translational Medicine and Therapeutics

  • Carsten Skarke, MD · University of Pennsylvania, Institute for Translational Medicine and Therapeutics

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-11-30
Primary Completion
2022-09-30
Completion
2022-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02502006 on ClinicalTrials.gov