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PlacEntal Acute Atherosis RefLecting Subclinical Atherosclerosis

NCT05500989 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 226

Last updated 2024-12-05

No results posted yet for this study

Summary

Pregnancy is considered a cardiovascular (CV) stress test, and complicated pregnancies are associated with an increased risk for cardiovascular disease (CVD) later in life. Moreover, it is known that often the pregnancy induced CV adaptation does not resolve completely after a short postpartum (PP) period and it is not clear whether these induced changes will resolve over a longer period of time (i.e. in the upcoming months/years after delivery).

Understanding the cardiac adaptation during pregnancy and the reversal process in the postpartum period, as well as the factors that influence this these processes, may provide us not only insight in this mechanism, but may help us in identifying factors that may be target points for modification.

Conditions

  • Pre-Eclampsia
  • HELLP Syndrome
  • Intrauterine Growth Restriction
  • Pregnancy

Sponsors & Collaborators

  • Maastricht University Medical Center

    lead OTHER

Principal Investigators

  • Marc Spaanderman, MD, PhD · Maastricht University Medical Center

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-11-30
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05500989 on ClinicalTrials.gov