Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

NCT05492188 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2025-10-10

No results posted yet for this study

Summary

The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain. For this, the researchers are recruiting 15 individuals with neuropathic pain due to spinal cord injury to participate in the reflex training procedure. The study involves approximately 50 visits with a total study duration of about 6.5 months (3 months for baseline and training phases followed by 1 month and 3 month follow-up visits).

Conditions

  • Spinal Cord Injuries
  • Neuropathic Pain
  • Neurological Injury
  • Pain

Interventions

BEHAVIORAL

Operant Conditioning of Cutaneous Reflexes

This is a training intervention in which people with a spinal cord injury are trained to change (increase or decrease) the activity of a certain spinal reflex. By changing this reflex, it is hypothesized that individuals can reduce pain due to spinal cord injury.

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED
  • Medical University of South Carolina

    lead OTHER

Principal Investigators

  • Aiko Thompson, PhD · Medical University of South Carolina

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-03-27
Primary Completion
2026-10-01
Completion
2026-10-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05492188 on ClinicalTrials.gov