Tau And Connectomics In TES Study
NCT05490576 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2024-02-28
Summary
This pilot study aims to assess if participants that meet the criteria for a TES diagnosis have a specific tau deposition profile on PET scanning using the PET tau binding ligand - \[18F\] PI-2620. It is hoped this study will highlight potential diagnostic tests of TES diagnosis, the in-life correlate of CTE.
Conditions
- Chronic Traumatic Encephalopathy
- Traumatic Encephalopathy
- Head Injury Trauma
- Cognitive Impairment
- Neurodegenerative Diseases
Interventions
- RADIATION
-
[18F] PI-2620 Tau Ligand
Tau binding ligand
Sponsors & Collaborators
-
Omniscient Neurotechnology
collaborator INDUSTRY -
Life Molecular Imaging GmbH
collaborator INDUSTRY -
Macquarie University, Australia
lead OTHER
Principal Investigators
-
Rowena Mobbs, MBBS, PhD · MQ Health
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 40 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-02-03
- Primary Completion
- 2023-05-30
- Completion
- 2024-12-31
Countries
- Australia
Study Locations
More Related Trials
-
PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
NCT05456503 ·Status: RECRUITING ·Phase: PHASE3
-
Topography Staging and Dual Phase Image Quantification of Tau PET in Cognitive Impairment Subjects
NCT04169126 ·Status: UNKNOWN ·Phase: PHASE2
-
Longitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants
NCT02640092 ·Status: COMPLETED ·Phase: PHASE1
-
Tau PET in Imaging and Cognition: Healthy Adults From 55-90
NCT03372317 ·Status: RECRUITING
-
Evaluating the Relationship Between Tau PET Imaging and CSF Biomarkers of AD (Alzheimer Disease) in Humans
NCT03287765 ·Status: COMPLETED
-
The DIAGNOSE-CTE Research Project
NCT02798185 ·Status: COMPLETED
-
[18F]PI-2620 Phase 3 Histopathological Study
NCT05641688 ·Status: RECRUITING ·Phase: PHASE3
-
Tau Imaging of Chronic Traumatic Encephalopathy
NCT02191267 ·Status: COMPLETED ·Phase: PHASE2
-
Health and Aging Brain Study: Health Disparities Tau Positron Emission Tomography (PET) Scan Study
NCT05076331 ·Status: UNKNOWN
-
Novel Neuroimage Study in Tauopathies With Parkinsonism
NCT03386669 ·Status: COMPLETED ·Phase: PHASE2
-
Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations
NCT02676843 ·Status: COMPLETED ·Phase: PHASE2
-
F 18 T807 Tau PET Imaging in Dominantly Inherited Alzheimer's Network (DIAN Project)
NCT02414178 ·Status: ENROLLING_BY_INVITATION
-
PPMI Tau PET Imaging
NCT04906590 ·Status: COMPLETED ·Phase: PHASE2
-
Linking Tau PET to Medial Temporal Lobe Subregions With High Resolution MRI
NCT04251130 ·Status: ACTIVE_NOT_RECRUITING
-
Evaluation of [18F]MNI-815 as a Potential PET Radioligand for Imaging Tau Protein in the Brain of Patients With Tauopathies
NCT02531360 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
PET Tau - Neurodegenerative Disease Imaging
NCT03143374 ·Status: RECRUITING ·Phase: PHASE2/PHASE3
-
FDDNP Protocol for Visualizing Brain Proteinopathies to Assist in the Diagnosis of Persons With Suspected CTE and AD
NCT04311281 ·Status: WITHDRAWN
-
[18F]NIDF PET Imaging in Tau-related Diseases
NCT07306598 ·Status: RECRUITING
-
Tau PET Imaging in the NACC Study Cohort
NCT03189485 ·Status: ACTIVE_NOT_RECRUITING
-
18F-PM-PBB3 PET Study in Tauopathy Including Alzheimer's Disease, Other Dementias and Normal Controls
NCT03625128 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Evaluation of Tau Protein in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants
NCT03239561 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Beta Amyloid PET/CT in Various Aβ-Related Disease
NCT06725706 ·Status: RECRUITING
-
Cohort Study of Blood Biomarkers for TES
NCT04928534 ·Status: COMPLETED
-
Tau Protein and SV2a Imaging in Patients With Tau Protein-related Diseases
NCT05260151 ·Status: UNKNOWN
-
PET Imaging in Chronic Traumatic Encephalopathy
NCT02211820 ·Status: COMPLETED