MedTrace Logo

Clinical Impact of Red Cell Storage Age

NCT05482737 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 33000

Last updated 2024-10-03

No results posted yet for this study

Summary

The recent four RCTs evaluating effects of RBC storage age on morbidity and mortality found no statistically significant adverse effects of longer stored RBC compared to shorter storage ages. Unfortunately, none of these RCTs had sufficient numbers of subjects receiving RBC at either storage age extreme to identify consequences of RBC transfusion at these limits. To better investigate effects of RBC storage age on clinical outcomes, this study will perform secondary meta-analyses of merged common patient data elements -individual patient data (IPD) meta-analysis (IPDMA) - from the nearly 33,000 subjects enrolled in the four RCTs.

Conditions

  • RBC Transfusions

Interventions

OTHER

no intervention

This is an observational retrospective study (meta-analysis)

Sponsors & Collaborators

Principal Investigators

  • Marie Steiner, MD · University of Minnesota

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-07-01
Primary Completion
2023-08-01
Completion
2024-08-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05482737 on ClinicalTrials.gov