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Biological Parameters Changes After Autologous Blood Transfusion of Red Blood Cells (200 ml) in Healthy Volunteers.

NCT03889834 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2026-04-23

No results posted yet for this study

Summary

The purpose of this study is to evaluate if differences between samples of subjects obtained before autologous blood transfusion or samples of non-transfused subjects and samples of subjects after autologous blood transfusion can be identified. Analyses performed will focus on the morphological and biochemical parameters of red blood cells and associated microparticles. The final goal would be to find markers of autologous blood transfusion, that could be used to identify such doping practice.

Conditions

  • The Focus is on the Detection of the Consequences of Autologous Blood Transfusion in Healthy Volunteers

Interventions

PROCEDURE

Autologous Blood Transfusion

Autotransfusion of packed red blood cells (200 ml) stored at 4 or -80°C for 33 days

OTHER

No transfusion

no transfusion

Sponsors & Collaborators

  • Laboratoire antidopage français (LADF)

    collaborator UNKNOWN

  • World Anti-Doping Agency

    collaborator OTHER

  • GR-Ex executive comitee

    collaborator UNKNOWN

  • Institut National de la Santé Et de la Recherche Médicale, France

    collaborator OTHER_GOV

  • Etablissement Français du Sang

    collaborator OTHER

  • URC-CIC Paris Descartes Necker Cochin

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Olivier HERMINE, MD, PhD · Assistance Publique-Hôpitaux Paris

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-01-25
Primary Completion
2025-03-27
Completion
2026-04-02

Countries

  • France

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03889834 on ClinicalTrials.gov