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Reproductive Outcomes After a Previous Episode of Tubal Ectopic Pregnancy in Patients Managed Expectantly and Surgically

NCT05479786 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 312

Last updated 2022-08-02

No results posted yet for this study

Summary

Although ectopic pregnancy was considered a leading cause of first-trimester maternal mortalities, current technological improvements allowed early diagnosis and opened a door for applying less invasive approaches. A tubal pregnancy could be managed either expectantly, medically, or surgically. The expectant management of ectopic pregnancy relies on the fact that a considerable proportion of ectopic gestations terminate by spontaneous tubal abortion. This approach is usually kept for stable cases with a small gestational sac and low beta-human chorionic gonadotropin (beta-HCG) serum levels. For hemodynamically unstable patients, higher levels of beta-HCG, and larger gestational sacs, surgery is often considered as the treatment of choice (16).

Considering this background, the study aims to analyze the subsequent natural reproductive outcomes of patients that had a previous tubal ectopic pregnancy and were managed either expectantly or surgically. Moreover, it amis to determine the factors that could influence the fertility potential of these patients in each treatment group.

Conditions

Interventions

OTHER

Expectant management

Follow-up with beta-HCG dosages and transvaginal ultrasound scans

PROCEDURE

Salpingectomy

Removal of the affected Fallopian tube by laparoscopy

PROCEDURE

Salpingostomy

Removal of the ectopic pregnancy from the Fallopian tube, without removing the whole Fallopian tube, by laparoscopy

Sponsors & Collaborators

  • University of Debrecen

    collaborator OTHER

  • Damascus University

    collaborator OTHER

  • University of Palermo

    lead OTHER

Principal Investigators

  • Antonio Simone Laganà, M.D., Ph.D. · University of Palermo

  • Antoine Naem, M.D. · Damascus University

  • Péter Török, M.D. · University of Debrecen

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-01
Primary Completion
2020-12-31
Completion
2020-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05479786 on ClinicalTrials.gov