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Qualitative and Functional Investigation of Lipids in Patients With SARS-CoV2 Infection - In Search of Atherogenic Sequelae

NCT05476224 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 228

Last updated 2023-10-02

No results posted yet for this study

Summary

Currently, the world is facing a SARS-CoV2 coronavirus epidemic, which is responsible for COVID-19. In France, this virus has already infected several million people and is responsible for the death of more than 127,000.

Infection is associated with a higher number of cardiovascular events (myocardial infarction, stroke, cardiac arrhythmia, thrombosis ...) in the short and medium term after infection. The long-term complications of this infection are not yet known and are the subject of research in France and in the world.

In order to investigate the possible long term sequelae of this virus infection, this research aims to evaluate the potential cholesterol abnormalities caused by COVID-19, which could play a significant role in the increase of cardiovascular risk in affected patients.

A total of 180 analysable participants will be recruited in this study. They will be divided into four groups of participants that will be compared to one another:

* 30 participants who were infected with SARS-CoV2 with no or few signs and did not require hospitalization.
* 30 participants who were infected with SARS-CoV2 and whose severity of illness required hospitalization in a COVID unit
* 30 participants who were infected with SARS-CoV2 and required intensive care hospitalization due to severity of illness.
* 90 participants who were not infected with SARS-CoV2.

For each participant, the study will last approximately 1 hour, the time to fill out the consent forms, to answer a few questions about their current medical history and finally to take a blood sample for lipid measurements.

Conditions

  • SARS-CoV2 Infection

Interventions

BIOLOGICAL

Blood sample of 30 ml

The parameters analyzed on this blood sample: Fasting blood glucose, HbA1C, creatinine, creatinine clearance (MDRD), fasting lipid profile (total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides.

Sponsors & Collaborators

  • Centre Hospitalier Universitaire Dijon

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-06-14
Primary Completion
2023-04-12
Completion
2023-04-12

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05476224 on ClinicalTrials.gov