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Post-radiotherapy Rhinosinusitis in Children

NCT05454163 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2026-05-22

No results posted yet for this study

Summary

Chronic rhinosinusitis (CRS) is a frequent complication of facial cancer treatment, mainly related to radiotherapy. However, while radiological involvement is frequent, clinical expression seems less important.

Few studies have investigated the incidence of this condition in the pediatric population while its evolution seems to be very chronic even if a partial improvement may occur with time.

Our objective is therefore to study the impact of CSR in children treated for cancer of the cervicofacial region, to evaluate its incidence and medium-term evolution in order to determine whether it is necessary to set up a specific follow-up in these patients.

The clinical impact of CSR is assessed by a specific SNOT 22 questionnaire in children treated for a head-neck mesenchymal malignancy in comparison with a control population consisting of children treated for a mesenchymal malignancy of non-head-neck location.

Conditions

  • Pediatric Cancer
  • Chronic Sinusitis

Interventions

OTHER

SNOT 22 questionnaire

22 items, score between 0 and 5; sum, minimum = 0, maximum = 110; higher score = higher impact on quality of life)

Sponsors & Collaborators

  • Centre Oscar Lambret

    collaborator OTHER

  • University Hospital, Lille

    lead OTHER

Principal Investigators

  • Pierre Fayoux, MD,PhD · University Hospital, Lille

Eligibility

Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-01
Primary Completion
2023-10-01
Completion
2023-10-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05454163 on ClinicalTrials.gov