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Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery

NCT05453929 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 230

Last updated 2025-01-03

No results posted yet for this study

Summary

The effect of deep neuromuscular blockade (NMB) during spine surgery reduced postoperative pain and bleeding in recent studies. Therefore by reducing these two factors, which were the contributing factors for postoperative delirium, deep NMB is expected to reduce the postoperative delirium. This study was designed to determine whether the deep NMB lowered the incidence of delirium after lumbar surgery.

Conditions

  • Lumbar Spine Disease

Interventions

DRUG

Rocuronium for deep NMB

Deep neuromuscular blockade will be maintained using continuous infusion of rocuronium.

DRUG

Rocuronium for moderate NMB

Moderate neuromuscular blockade will be maintained using continuous infusion of rocuronium.

Sponsors & Collaborators

  • Korea University Guro Hospital

    lead OTHER

Principal Investigators

  • Seok Kyeong Oh, MD, PhD · Korea University Guro Hospital

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-16
Primary Completion
2024-12-20
Completion
2025-01-02

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05453929 on ClinicalTrials.gov