iTBS Can Increase Frontal Dopamine Release in PET Dopamine Imaging.
NCT05448430 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2022-07-07
Summary
Aim: 1. To confirm that patients with predominant negative symptoms in schizophrenia have deficits in frontal cortical dopamine release when compared with healthy control and patients with positive symptoms.
2\. Our previous study found patients with negative symptoms have more possibilities to have disorders in glucose metabolism, we wonder whether dopamine release, negative symptoms or glucose metabolism can be improved by iTBS.
Study design: Case control study.
Conditions
Interventions
- DEVICE
-
Theta burst stimulation
a new paradigm of high frequency repetitive transcranial magnetic stimulation
Sponsors & Collaborators
-
Central South University
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- SCREENING
- Masking
- DOUBLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-07-15
- Primary Completion
- 2024-07-01
- Completion
- 2024-07-01
Countries
- China
Study Locations
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