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Assessing the Repeatability of NT-proBNP Testing Using Laboratory and Point of Care Testing in PAH

NCT05421949 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2023-08-14

No results posted yet for this study

Summary

The purpose of this study is to examine N-terminal pro brain natriuretic peptide (NT-proBNP) and brain natriuretic peptide (BNP) biomarkers in a number of different settings including assessing the repeatability of laboratory and point of care testing (POCT), the effect of a time delay and exercise have on laboratory measurements. Also to compare the clinical and analytical performances of NT-proBNP and BNP POCT samples across the spectrum of disease severity and finally assess whether POCT in PAH can detect change in patients commencing or escalating PAH treatment.

Conditions

  • Pulmonary Artery Hypertension

Interventions

OTHER

Exercise group

Incremental Shuttle Walking Test

Sponsors & Collaborators

  • Actelion

    collaborator INDUSTRY

  • Sheffield Teaching Hospitals NHS Foundation Trust

    lead OTHER

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-02-19
Primary Completion
2022-08-30
Completion
2022-08-30

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05421949 on ClinicalTrials.gov