Clinical Value of Metagenomic Sequencing in Neonatal Sepsis

Summary

This study aimed to enroll 2000 neonatal patients with suspected sepsis or clinical diagnosed sepsis. These patients will undergo both conventional methods and metagenomics sequencing to detect the pathogenic microorganisms of sepsis. The purpose of this study was to assess the clinical value of metagenomics sequencing for the diagnosis and treatment of neonatal sepsis.

Conditions

• Neonatal Sepsis

Sponsors & Collaborators

• Quanzhou Women's and Children's Hospital

  collaborator UNKNOWN

• Shengjing Hospital

  collaborator OTHER

• Jiangxi Maternal and Child Health Hospital

  collaborator OTHER

• Northwest Women's and Children's Hospital, Xi'an, Shaanxi

  collaborator OTHER

• Nanjing Maternity and Child Health Care Hospital

  collaborator OTHER

• The First Hospital of Jilin University

  collaborator OTHER

• Hunan Children's Hospital

  collaborator OTHER_GOV

• Henan Provincial People's Hospital

  collaborator OTHER

• Tianjin Central Hospital of Gynecology Obstetrics

  collaborator OTHER

• Jiangxi Children's Hospital

  collaborator UNKNOWN

• Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region

  collaborator OTHER

• Xinjiang Children's Hospital

  collaborator UNKNOWN

• Shenzhen Maternity and Child Healthcare Hospital

  collaborator UNKNOWN

• Children's Hospital of Nanjing Medical University

  collaborator OTHER

• Gansu Provincial Maternal and Child Health Care Hospital

  collaborator OTHER

• Kunming Children's Hospital

  collaborator OTHER

• Fujian Provincial Maternity and Children

  collaborator UNKNOWN

• Zhuhai Women and Children's Hospital

  collaborator UNKNOWN

• Xiamen Children's Hospital

  collaborator OTHER

• Children's Hospital Affiliated to Shandong University

  collaborator UNKNOWN

• Henan Maternal and Child Health Care Hospital

  collaborator UNKNOWN

• Wuhan Children's Hospital

  collaborator OTHER

• Children's Hospital of Fudan University

  lead OTHER

Principal Investigators

• Wenhao Zhou, Doctor · Children's Hospital of Fudan University

Eligibility

Min Age

0 Days

Max Age

28 Days

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-04-01

Primary Completion

2022-12-01

Completion

2022-12-30

Countries

• China

Study Locations