The Effect of RECO-18 on Infertile Women Undergoing in Vitro Fertilization-embryo Transfer
NCT05412147 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2022-06-09
Summary
How to improve the fertility of infertile women has become a hot topic in the field of assisted reproduction. Animal experiment has shown that RECO-18 significantly improved the female fertility in mice, and the specific mechanism was related to reducing follicular atresia, promoting follicle development and improving oocyte quality. Therefore the investigators aim to conduct a pilot study to explore the effect of RECO-18 in infertile women undergoing assisted reproduction treatment. This study is a prospective, randomized, controlled clinical study. The treatment group takes RECO-18 while the control group takes the multi-vitamins. The primary indicator is the ongoing pregnancy rate at 12 weeks' gestation; the secondary indicators are the number of oocytes retrieved, the normal fertilization rate and the rate of high quality embryos, implantation rate, clinical pregnancy rate, and early miscarriage rate.
Conditions
- Fertility Disorders
- Infertility, Female
Interventions
- DIETARY_SUPPLEMENT
-
RECO-18
4 pills daily, oral
- DIETARY_SUPPLEMENT
-
Multi-vitamins
one tablet daily, oral
Sponsors & Collaborators
-
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
lead OTHER
Principal Investigators
-
Dongzi Yang, doctor · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
-
Hui Chen, doctor · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
-
Ruiqi Li, doctor · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
-
Xiaoli Chen, doctor · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
-
Lin Li, doctor · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
-
Ping Pan, doctor · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
-
Jia Huang, doctor · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 40 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-31
- Primary Completion
- 2023-04-30
- Completion
- 2023-04-30
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