Assessment of Safety and Immunogenicity of R21/Matrix-M™ in African Children Living With HIV
NCT05385510 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 122
Last updated 2026-02-20
Summary
A Phase Ib trial to evaluate the safety and immunogenicity of R21/Matrix-M™ in African children living with HIV
Conditions
Interventions
- BIOLOGICAL
-
R21/Matrix-M™
Adjuvanted malaria vaccine
Sponsors & Collaborators
-
MRC/UVRI and LSHTM Uganda Research Unit
collaborator OTHER -
University of Oxford
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 5 Months
- Max Age
- 36 Months
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-01-10
- Primary Completion
- 2025-09-03
- Completion
- 2025-09-03
Countries
- Uganda
Study Locations
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