MedTrace Logo

Feasibility of Identifying, Enrolling and Following Acute and Early HIV-1 Infected Individuals.

NCT05372510 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2022-05-12

No results posted yet for this study

Summary

It is only between peak viremia and viral setpoint in natural acute HIV-1 infection that the immune response overwhelms viral replication resulting in a plasma viral load decline. The aim will be to characterize these immune responses, how they develop and their progeny. This will require the need to identify HIV-1 infected individuals before peak viremia and follow them to post viral setpoint.

This protocol describes a pilot study to evaluate the feasibility of identifying, enrolling and following acute and early HIV-1 infected individuals from voluntary counselling and testing centres in Masaka, Bukomansimbi, Kalungu, Lwengo, Sembababule and Lyantonde districts.

Conditions

  • Acute Human Immunodeficiency Virus Type I Infection

Sponsors & Collaborators

  • International AIDS Vaccine Initiative

    collaborator NETWORK

  • MRC/UVRI and LSHTM Uganda Research Unit

    lead OTHER

Principal Investigators

  • ANDREW OBUKU, PhD · London School of Hygiene and Tropical Medicine

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-02-17
Primary Completion
2022-12-31
Completion
2022-12-31

Countries

  • Uganda

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05372510 on ClinicalTrials.gov