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Substantivity of Oral Rinses: Comparative Study

NCT05365737 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2022-05-11

No results posted yet for this study

Summary

A desirable quality of mouthrinses is substantivity an intrinsic feature of some molecules. Substantivity requires the adsorption of the agent on the oral surfaces and subsequently antimicrobial activity bacteriostatic along following hours. This work aims to quantitatively determine the substantivity of (i) a single o-Cymen-5-ol plus CPC oral rinse, (ii) a, CPC oral rinse and (iii) a o-Cymen-5-ol mouthwash on the salivary microbiota up to 4 h after their application.

Conditions

  • Prevention & Control

Interventions

OTHER

Oral rinse

Participants use mouthwasher for a given time.

OTHER

Saliva harvest

Non-stimulated saliva harvesting

Sponsors & Collaborators

  • University of Barcelona

    lead OTHER

Principal Investigators

  • Miguel Viñas, PhD · University of Barcelona-Spain-

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-01-01
Primary Completion
2022-01-25
Completion
2022-02-03

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05365737 on ClinicalTrials.gov