Phase I Study of HRS-3738 in Recurrent and Refractory Non-Hodgkin's Lymphoma and Multiple Myeloma
NCT05363800 · Status: UNKNOWN · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 198
Last updated 2022-07-29
Summary
This study is an open-label, multicenter Phase I clinical trial to evaluate the safety, tolerability, pharmacokinetics and efficacy of HRS-3738 in patients with recurrent and refractory Non-Hodgkin's lymphoma and multiple myeloma.
Conditions
- Recurrent and Refractory Non-Hodgkin's Lymphoma and Multiple Myeloma
Interventions
- DRUG
-
HRS-3738
HRS-3738 will be administrated per dose level in which the patients are assigned.
Sponsors & Collaborators
-
Jiangsu HengRui Medicine Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-17
- Primary Completion
- 2024-10-30
- Completion
- 2024-12-30
Countries
- China
Study Locations
More Related Trials
-
HMPL-760 in Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
NCT05190068 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of GNC-038 Injection in Patients With Relapsed or Refractory NK/ T-cell Lymphoma, AITL, and Other NHL
NCT05627856 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Phase I Clinical Study of JS203 in Patients With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
NCT05618327 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
TR115 in Patients With Relapsed / Refractory Non-Hodgkin's Lymphoma or Advanced Solid Tumors
NCT05650580 ·Status: RECRUITING ·Phase: PHASE1
-
Recombinant Humanized Anti-CD47/PD-1 Bifunctional Antibody HX009 in Patients With Relapsed/Refractory Lymphoma
NCT05189093 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors
NCT05892718 ·Status: RECRUITING ·Phase: PHASE1
-
Efficacy and Safety of SHR0302 in Patients With Relapsed/Refractory Peripheral T/NK Cell Lymphoma
NCT05900089 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
A Study of GFH009 in Combination With Zanubrutinib in Subjects With Relapsed or Refractory DLBCL
NCT06375733 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Phase I Clinical Study of GNC-038 in Patients With Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
NCT04606433 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Safety and Efficacy of EX103 in Subjects with Relapsed/Refractory CD20-Positive Non-Hodgkin Lymphoma
NCT06021678 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
NCT06470438 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS
NCT03573310 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate Efficacy and Safety of HH2853 in Relapsed/Refractory Peripheral T-cell Lymphoma
NCT06909877 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Clinical Study of HiR+X Therapy for Newly Diagnosed Elderly Patients with DLBCL Intolerant to Chemotherapy
NCT06758037 ·Status: RECRUITING ·Phase: PHASE2
-
APG-1252 Monotherapy or in Combination With Other Therapeutic Agent in Subjects With Relapsed or Refractory Non-Hodgkin Lymphoma
NCT05186012 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Clinical Study of HMPL-689 for Relapsed/Refractory Marginal Zone Lymphoma and Follicular Lymphoma
NCT04849351 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of JNJ-67856633 in Participants With Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)
NCT03900598 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of GRC 54276 in Participants With Advanced Solid Tumors and Lymphomas.
NCT05878691 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Study of MGCD0103 Given Three Times Weekly in Patients With Relapsed and Refractory Lymphoma
NCT00359086 ·Status: COMPLETED ·Phase: PHASE2
-
Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma (NHL)
NCT04533581 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Phase I/II Study of CM355 in Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL)
NCT05210868 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Chidamide Combined With Linperlisibon for the Treatment of Refractory/Relapsed Follicular Lymphoma
NCT06158386 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of HMPL-689 in Patients With Lymphomas Failed of Standard of Care or no Standard of Care Existed
NCT03128164 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of SHC014748M in Patients With Relapsed or Refractory Peripheral T Cell Lymphoma
NCT04470141 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of MGCD0103 Given Three-Times Weekly in Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma
NCT00323934 ·Status: COMPLETED ·Phase: PHASE1