MedTrace Logo

A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation

NCT05357690 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 220

Last updated 2025-05-14

No results posted yet for this study

Summary

The purpose of this study is to test if a nerve block procedure called a stellate ganglion block can help decrease the chance of atrial fibrillation after surgery. Atrial fibrillation is the abnormal, fast beating of the upper chambers of the heart. Stellate ganglion blockade has shown to decrease other types of abnormal heart rhythms as well as decrease the chance of atrial fibrillation.

Conditions

Interventions

PROCEDURE

Stellate ganglion block

Ultrasound guided injection into the stellate ganglion performed in the right side of the neck in a sterile fashion.

DRUG

Bupivacaine

10 mL of 0.5% without epinephrine injected in the plane of the right stellate ganglion

DRUG

Placebo

10 mL of saline injected in the plane of the right stellate ganglion

Sponsors & Collaborators

Principal Investigators

  • Erica Wittwer, MD · Mayo Clinic

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-19
Primary Completion
2026-04-30
Completion
2026-12-31
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05357690 on ClinicalTrials.gov