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PROFILE-MI - The FAPI Fibrosis Study

NCT05356923 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2024-05-17

No results posted yet for this study

Summary

The investigators here propose to investigate the timing and pattern of myocardial fibrosis activity following acute myocardial infarction using hybrid 68Ga-FAPI positron emission tomography and cardiovascular magnetic resonance. The investigators hypothesise that peak fibrosis activity will occur within 2-4 weeks of acute myocardial infarction and will predict subsequent scar formation and cardiac remodelling. Simultaneously, matrix remodelling and fibrosis activity in aortic and coronary atheroma will be assessed enabling the exploration of the presence of unstable atheroma.

Conditions

Interventions

RADIATION

68Gallium FAPI PET/MR scan

68Gallium FAPI PET/MR scan

Sponsors & Collaborators

  • University of Edinburgh

    lead OTHER

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-04-21
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05356923 on ClinicalTrials.gov