Outcome of Treatment of Uveitis With Biologic Drugs in Resistant Cases Vogt-koyanagi-Harada Disease
NCT05349747 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2022-04-27
Summary
* Reviewing the characteristics of patients with uveitis caused by Vogt-Koyanagi-Harada Syndrome treated at Assiut University Hospital at the Department of Ophthalmology and Department of Rheumatology, Physical Medicine, and Rehabilitation including the ocular features in terms of uveitis location, type and complications and systemic features of those subjects who showed an inadequate response to conventional immunomodulatory drugs.
* Assess the results of treatment with biologic drugs, including rates of failure and adverse events. This will help uveitis specialists to reach a conclusion about the best treatment protocols for Uveitis in Vogt-Koyanagi-Harada Syndrome in our population in terms of safety, efficacy, and cost-effectiveness.
Conditions
- Uveitis
Interventions
- BIOLOGICAL
-
Biologic drugs
Assess the results of treatment with biologic drugs
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
Salma Safwat, Master · Assiut University
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-04-30
- Primary Completion
- 2024-04-30
- Completion
- 2024-08-31
More Related Trials
-
Observation on the Treg in the Uveitis Patients
NCT01306474 ·Status: COMPLETED
-
Evaluation of a Standardized Strategy for Uveitis Etiological Diagnosis
NCT01162070 ·Status: COMPLETED ·Phase: NA
-
Intravitreal Adalimumab in Refractory Diabetic Retinopathy, Choroidal Neovascularization or Uveitis: A Pilot Study
NCT00855608 ·Status: UNKNOWN ·Phase: PHASE1
-
Phase 2 Study of MM-093 to Treat Patients With Uveitis
NCT00444743 ·Status: COMPLETED ·Phase: PHASE2
-
Leflunomide to Treat Uveitis
NCT00001863 ·Status: COMPLETED ·Phase: PHASE2
-
Minocycline for Chronic Autoimmune Uveitis
NCT05474729 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Efficacy and Safety of Adalimumab Plus Medium Dose Oral Glucocorticosteroid for Refractory Behçet's Uveitis
NCT05105347 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Immune Responses to Antigens in Non-infectious Eye Inflammatory Diseases
NCT00357071 ·Status: COMPLETED
-
Analysis of Eye Tissue
NCT00001224 ·Status: COMPLETED
-
Efficacy Study of Ranibizumab on Patients With Age-related Macular Degeneration.
NCT01831947 ·Status: COMPLETED ·Phase: PHASE4
-
Safety, Tolerability, and Efficacy of AEB071 in the Treatment of Uveitis
NCT00615693 ·Status: COMPLETED ·Phase: PHASE2
-
Multicenter Clinical Study of Anti-VEGF Treatment on High Risk Diabetic Retinopathy (DR)
NCT03452657 ·Status: UNKNOWN ·Phase: PHASE3
-
Treatment FOr Corticosteroid Dependent UveitiS
NCT06258915 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Intraocular Cytokines in Non-responders to Ranibizumab Treatment for Neovascular AMD
NCT02218177 ·Status: COMPLETED
-
A Study of the Criteria Establishing the Need for Re-treatment With Ranibizumab Upon Relapse in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia.
NCT02034006 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implant vs Standardized Therapy
NCT00468871 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Intravitreal Ranibizumab in Recurrent ROP
NCT04539106 ·Status: COMPLETED
-
Targeting Immunosuppressive Treatment for Non-infectious Uveitis Using Aqueous Humor Cytokine Profiles
NCT07262437 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory Disease
NCT00331331 ·Status: COMPLETED
-
Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Agerelated Macular Degeneration (AMD) Who Received Anti-VEGF Agents (IRIS Registry)
NCT05110209 ·Status: COMPLETED
-
Extension Study to Assess Safety and Efficacy of AIN457 in Patients With Active Non-infectious Uveitis
NCT01103024 ·Status: WITHDRAWN ·Phase: PHASE3
-
Analysis of naïve Patients With Age-related Macular Degeneration Neovascular Type and Treated With Ranibizumab (Lucentis®) in Treat-and-extend at the CHU Brugmann.
NCT04988178 ·Status: COMPLETED
-
A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants
NCT07218770 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of LX211 in Clinically Quiescent Non-infectious Intermediate, Anterior and Intermediate, Posterior or Pan-Uveitis
NCT00404742 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Non-infectious Intermediate and Posterior Uveitis Associated Macular Edema With Intravitreal Methotrexate
NCT01314417 ·Status: TERMINATED ·Phase: PHASE1/PHASE2