The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on the Immune Function for Cirrhosis Patients
NCT05338294 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2025-05-28
Summary
In this study, the investigators compared the improvement of immune function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative immune function and improve patient prognosis.
Conditions
- Cirrhosis, Liver
- Splenectomy; Status
Interventions
- PROCEDURE
-
Laparoscopic splenectomy and azygoportal disconnection
Laparoscopic splenectomy and azygoportal disconnection is performed by the same surgical team.
Sponsors & Collaborators
-
Northern Jiangsu People's Hospital
lead OTHER
Principal Investigators
-
Guo-Qing Jiang, MD · Clinical Medical College, Yangzhou University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-03-01
- Primary Completion
- 2025-07-31
- Completion
- 2025-07-31
Countries
- China
Study Locations
More Related Trials
-
Precision Medicine to Predict the Trajectory of Liver Cirrhosis: Prospective Cohort Study
NCT05899309 ·Status: UNKNOWN
-
Infections in Hospitalized Cirrhotic Patients
NCT03137719 ·Status: COMPLETED
-
Bacterial Infections in Cirrhotic Patients With Acute Severe Liver Injury
NCT03204591 ·Status: UNKNOWN
-
Investigation of the Prevalence of Hepatopulmonary Syndrome in Cirrhosis Patients Caused by Hepatitis B in Western China
NCT03435406 ·Status: UNKNOWN
-
Anticoagulation Therapy After Splenectomy in Cirrhosis Patient
NCT04397289 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Mechanism of TIPS to Improve Sarcopenia
NCT06794853 ·Status: RECRUITING
-
Assessment of Severity of Liver Disease Before Surgery
NCT05503836 ·Status: UNKNOWN
-
Hypersplenism in Patients With Liver Cirrhosis and Portal Hypertension
NCT03269877 ·Status: UNKNOWN
-
Effect of Transjugular Intrahepatic Portosystemic Shunt on Oxygenation in Cirrhotic Patients With Hepatopulmonary Syndrome
NCT02148536 ·Status: COMPLETED
-
Predictive Models of Hepatic Decompensation and Survival Outcomes in Pediatric Patients With Cirrhosis
NCT05181332 ·Status: UNKNOWN
-
A Clinical Trial of the Vessel Sealing System (LigaSure) in Azygoportal Disconnection and Splenectomy in Patients With Portal Hypertension
NCT00965744 ·Status: COMPLETED ·Phase: PHASE4
-
Application of in Vivo Splitting Technique in Adult Liver Transplantation
NCT06925828 ·Status: ACTIVE_NOT_RECRUITING
-
Albumin Infusion in Inpatients With Decompensated Cirrhosis
NCT05719051 ·Status: UNKNOWN
-
Magnetic Resonance Technics for the Assessment of Liver Function Before and After TIPS
NCT03933891 ·Status: UNKNOWN
-
Clinical Study of Hepatocyte Transplantation for Liver Cirrhosis
NCT04806581 ·Status: UNKNOWN ·Phase: PHASE1
-
Transitional Care Interventions for Patients With Cirrhosis Post-TIPS
NCT02877953 ·Status: UNKNOWN ·Phase: NA
-
To Study and Compare the Clinical Course and Development of Organ Failure in Severe Acute Hepatitis Without Ascites, Non-cirrhotic and Cirrhotic Patients With Ascites [Acute on Chronic Liver Failure] and Acute Deterioration of Previously Decompensated Cirrhosis.
NCT02465619 ·Status: WITHDRAWN
-
Pattern and Short Term Outcomes of Renal Affection in Patients With Liver Cirrhosis in Al-Rajhi Liver Hospital
NCT06924294 ·Status: NOT_YET_RECRUITING
-
Impact of Splenic Artery Ligation in LDLT for Patients With Portal Hypertension
NCT04988100 ·Status: UNKNOWN ·Phase: NA
-
Analysis of Clinical Features of Chronic Liver Disease Complicated With Hepatopulmonary Syndrome
NCT05932927 ·Status: UNKNOWN
-
Apixaban Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal Disconnection
NCT05304455 ·Status: COMPLETED ·Phase: NA
-
Prognosis of Patients With Acute-on-chronic Liver Failure
NCT05393453 ·Status: UNKNOWN
-
Diet Management on Hepatic Encephalopathy of Patients With Variceal Bleeding After Intrahepatic Portosystemic Shunt Creation
NCT03372499 ·Status: UNKNOWN ·Phase: NA
-
Efficacy of High Dose Albumin Therapy in Improving Liver Transplant-free Survival in Patients With Acute Decompensation of Cirrhosis
NCT05956197 ·Status: UNKNOWN
-
The Effects Of Remote Organ Ischemic Preconditioning On Systemic Inflammatory And Glycocalyx Integrity Parameters
NCT04216407 ·Status: COMPLETED ·Phase: NA