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Fitness and Fat Oxidation in Overweight Chinese, Indian and Malay Men

NCT05337111 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2022-04-20

No results posted yet for this study

Summary

South Asian men have lower cardiorespiratory fitness (CRF) than white men which is associated with a reduced capacity to oxidise fat during exercise. This is a risk factor for weight gain/regain. Whilst comparisons with Europeans are valuable, Asians are not a homogenous group and substantial differences in obesity and body fat partitioning exist with ethnicity. This cross-sectional pilot investigation aims to compare CRF and fat oxidation at rest and during exercise in Chinese, Indian and Malay men (from Singapore) with elevated BMI (23 -30 kg/m2). Forty-five men (15 each ethnicity) with elevated body mass index (23 -30 kg/m2) will complete testing in a fasted state on two separate mornings separated by ≥72 hours: (i) for a measure of CRF; and (ii) for a measure of fat oxidation at rest and during incremental exercise.

Conditions

  • Overweight and Obesity

Interventions

OTHER

Cardiorespiratory fitness test

Progressive submaximal exercise test on a treadmill to predict cardiorespiratory fitness

OTHER

Resting measure of fat oxidation

Use of ventilated hood attached to automated metabolic cart to measure substrate oxidation at rest

OTHER

Maximum fat oxidation test

Progressive exercise test to determine maximum fat oxidation during exercise

Sponsors & Collaborators

  • Ministry of Education, Singapore

    collaborator OTHER_GOV

  • Nanyang Technological University

    lead OTHER

Principal Investigators

  • Stephen F Burns, PhD · Nanyang Technological University

Eligibility

Min Age
21 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-07-01
Primary Completion
2020-03-30
Completion
2020-07-31

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05337111 on ClinicalTrials.gov