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Aortic Compression Trial to Reduce Blood Loss at Cesarean Section

NCT05312658 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2246

Last updated 2025-06-05

No results posted yet for this study

Summary

The goal of this clinical trial is to test if manual external aortic compression can prevent heavy blood loss in cesarean section. The main question\[s\] it aims to answer are:

1. Is external aortic compression effective?
2. Is external aortic compression safe?

Participants will receive preventive manual external aortic compression or no external aortic compression (standard care) immediately after the baby is out at cesarean section. Blood loss will be measured, as well as kidney function, hemoglobin, and hematocrit before and after the operation. Experienced discomfort will be assessed the day after surgery and breastfeeding and signs of depression will be assessed using questionnaires after 2 months.

Researchers will compare women with and without manual external aortic compression to see if there are differences in these outcomes.

Conditions

  • Post Partum Hemorrhage
  • Cesarean Section Complications
  • Anemia

Interventions

PROCEDURE

External aortic compression

External aortic compression by assistant in cesarean section.

Sponsors & Collaborators

Principal Investigators

  • Sophia Brismar Wendel, MD, PhD · Danderyd Hospital Karolinska Institutet, Sweden

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-12-01
Primary Completion
2027-12-31
Completion
2028-12-31

Countries

  • Sweden

Study Locations

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Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05312658 on ClinicalTrials.gov