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A Prospective Cluster-Randomized, Controlled Crossover Trial to Validate an Electronic "Resistance Calculator"

NCT05304221 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1500

Last updated 2024-07-31

No results posted yet for this study

Summary

Primary objective:

\- Our aim is to validate the "Shamir Resistance Calculator" in a prospective crossover trial, in order to shorten the time to initiation of appropriate antimicrobials among hospitalized septic patients.

Secondary objectives:

\- To evaluate the impact of using the "Shamir Resistance Calculator" with regards to:

* new acquisitions of multi-drug resistant organisms (MDRO)
* the empiric usage of broad-spectrum agents (e.g., carbapenems, vancomycin)
* acute Clostridiodes difficile infections
* In-hospital mortality.

Conditions

Interventions

OTHER

Shamir Resistance Calculator

An on-line calculator which is free and accessible from all devices, which may predict the risk of MDRO infection upon admission, and the risk of nosocomial XDRO infection during the hospitalization. The calculator contains only parameters that could be extracted bedside, at the first presentation of a septic patient, including the ability to conduct a complete assessment also among patients with reduced consciousness and/or cognition.

Sponsors & Collaborators

  • Hadassah Medical Organization

    collaborator OTHER

  • Dror MarChaim, MD

    lead OTHER_GOV

Principal Investigators

  • Dror MarChaim, M.D · Assaf-Harofeh Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-03
Primary Completion
2024-10-31
Completion
2025-01-31

Countries

  • Israel

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05304221 on ClinicalTrials.gov