Rocuronium and Supramaximal Stimulation
NCT05294523 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300
Last updated 2022-11-29
Summary
To shorten induction time, some anesthesiologist gives a priming dose of muscle relaxant before starting Neuromuscular Transmission monitor (NMT). To properly evaluate neuromuscular function during the surgury, baseline supramaximal stimulation of the monitored nerve is mandatory. Not knowing if the priming dose of muscle relaxant affects the supramaximal stimulation current setting, The investigators designed this study to find out.
Conditions
- Neuromuscular Blockade
Interventions
- PROCEDURE
-
Rocuronium priming dose
Add the priming dose of rocuronium after the first supramaximal stimulation data measured
Sponsors & Collaborators
-
Taipei Medical University Hospital
lead OTHER
Principal Investigators
-
Wei Chieh Lai, MD, MPH · Taipei Medical University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-12-20
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
Countries
- Taiwan
Study Locations
More Related Trials
-
Influence of Neuromuscular Block on Mask Ventilation
NCT01849211 ·Status: COMPLETED ·Phase: NA
-
Incidence and Severity of Residual Neuromuscular Blockade
NCT02660398 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Recovery From Rocuronium 1.2 mg/kg Followed by Sugammadex (Org 25969) 16 mg/kg at 3 Minutes With Recovery From Succinylcholine 1.0 mg/kg (19.4.303)(P05946)(MK-8616-026)
NCT00474253 ·Status: COMPLETED ·Phase: PHASE3
-
Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED)
NCT00751179 ·Status: COMPLETED ·Phase: PHASE3
-
Deep Neuromuscular Relaxation in Patients for Thoraco-laparoscopic Esophagectomy
NCT02320734 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Sugammadex During Transcranial Electrical Motor Evoked Potential Monitoring in Spinal Surgery
NCT04471376 ·Status: COMPLETED ·Phase: NA
-
Combined Use of Low-dose Sugammadex Plus Neostigmine Administered for Reversal of Rocuronium
NCT03328312 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Effect of Intercostal Nerve Block With Ropivacaine Combined With Mecobalamine on Chronic Pain After Thoracic Surgery
NCT04217213 ·Status: UNKNOWN ·Phase: NA
-
Effect of Magnesium on Dose of Rocuronium for Deep Neuromuscular Blockade
NCT04013243 ·Status: COMPLETED ·Phase: NA
-
Effects of Cisatracurium on Succinylcholine-induced Fasciculations and Myalgia
NCT02481193 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Intravenous Lidocaine on Serum miRNA-135a in Patients Undergoing Non-cardiac Surgery
NCT05503043 ·Status: UNKNOWN ·Phase: NA
-
Effects of Deep Neuromuscular Blockade on Intraoperative Respiratory Mechanics
NCT02185339 ·Status: COMPLETED ·Phase: PHASE4
-
Paraspinal Muscle Relaxation in Spine Surgery
NCT03318718 ·Status: COMPLETED ·Phase: NA
-
Impact of Deep Versus Standard Muscle Relaxation on Intra-operative Safety
NCT04124757 ·Status: COMPLETED ·Phase: NA
-
Effects of Methylprednisolone Plus Ropivacaine Infiltration Before Wound Closure on Laminoplasty or Laminectomy
NCT04493463 ·Status: COMPLETED ·Phase: PHASE4
-
Sugammadex After Continuous Infusion of Rocuronium During Sevoflurane and Propofol Anesthesia (P05949; MK-8616-028)
NCT00559468 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block
NCT02483611 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy, Safety and Pharmacokinetics of Sugammadex (Org 25969; MK-8616) at 3 Different Time Points After 0.6 mg/kg Esmeron® in Male Participants (P05940; MK-8616-020).
NCT03519854 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery
NCT05619848 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Effect of Pre-treatment With Magnesium Sulfate on the Duration of Deep Neuromuscular Blockade With Rocuronium
NCT02989272 ·Status: UNKNOWN ·Phase: PHASE4
-
Neuromuscular Block and Anesthetic Depth Monitoring
NCT02575443 ·Status: COMPLETED ·Phase: NA
-
Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)
NCT00298831 ·Status: COMPLETED ·Phase: PHASE3
-
Quality of Recovery After Reversal With Neostigmine or Sugammadex.
NCT02909439 ·Status: COMPLETED ·Phase: PHASE4
-
Does Depth of Neuromuscular Blockade (NMB) Affect Surgical Conditions in Obese Patients Undergoing Robotic Surgery
NCT03591289 ·Status: WITHDRAWN ·Phase: PHASE4
-
Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Intercostal Nerve Block for Chronic Post-thoracotomy Pain
NCT05556122 ·Status: UNKNOWN ·Phase: NA