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Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT

NCT05287204 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2024-03-28

No results posted yet for this study

Summary

The purpose of this study is to determine whether patients with acute kidney injury requiring renal replacement therapy have a higher incidence of muscle wasting than controls and whether the course of recovery is longer compared to controls.

Conditions

Interventions

DIAGNOSTIC_TEST

Musculoskeletal ultrasound

Ultrasound of rectus femoris to determine cross-sectional area, muscle thickness, echo intensity.

DIAGNOSTIC_TEST

Assessments of muscle strength and physical function

A battery of tests of physical function and muscle strength (see outcomes section for details).

DIAGNOSTIC_TEST

Metabolomics

Using metabolomic analysis, concentrations of amino acids and other important analytes will be measured in patient plasma and CRRT effluent

Sponsors & Collaborators

  • University of Iowa

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-29
Primary Completion
2023-09-30
Completion
2024-12-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05287204 on ClinicalTrials.gov