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Efficacy of Preoperative Radiotherapy for Non-responder Patients After Neoadjuvant Chemotherapy

NCT05274594 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 37

Last updated 2022-03-10

No results posted yet for this study

Summary

Neoadjuvant chemotherapy (NACT) is widely used for locally advanced breast cancer cases. As the key factor is to achieve pathologic complete response (pCR), several physicians tried administering radiotherapy before surgery to increase response rates. In this single center observational cohort study, we aim to present the initial results as complete response rates and complication rates of additional neoadjuvant radiotherapy (NART) after NACT.

Conditions

  • Breast Neoplasms
  • Radiotherapy; Complications
  • Survivorship
  • Breast Cancer

Interventions

RADIATION

Radiotherapy

Patients who are candidate for radiotherapy and received neoadjuvant chemotherapy for breast cancer were evaluated after neoadjuvant chemotherapy. Cases that do not have clinical response received radiotherapy before surgery in order to increase complete response.

Sponsors & Collaborators

  • Istanbul Breast Society

    lead OTHER

Principal Investigators

  • Mahmut Müslümanoğlu, Prof. Dr. · MD,FEBS,FACS

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2020-01-01
Completion
2022-01-01

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05274594 on ClinicalTrials.gov