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MINDS Imaging Ancillary Study

NCT05270356 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 195

Last updated 2025-10-31

No results posted yet for this study

Summary

This study is an ancillary study to the NHLBI-funded Pediatric Heart Network (PHN) "Multi-Institutional Neurocognitive Discovery Study" (MINDS) in Adult Congenital Heart Disease (ACHD). The MINDS-ACHD" study will recruit 500 complex CHD patients between18-30 years old. The investigators propose to quantitate multi-modal neuroimaging biomarkers (brain injury, structure and physiology) which are not only important components of brain and cognitive reserve but can be predictive of neurocognitive decline and early onset of dementia in the aging non-CHD population.

Conditions

  • Adult Congenital Heart Disease

Interventions

OTHER

MRI

Magnet Resonance Imaging of the Brain without Contrast

Sponsors & Collaborators

  • Boston Children's Hospital

    collaborator OTHER

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • Ashok Panigrahy, MD · University of Pittsburgh

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-05-27
Primary Completion
2025-05-31
Completion
2025-05-31

Countries

  • United States
  • Canada

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05270356 on ClinicalTrials.gov