A Study to Evaluate the Value of Circulating Tumour DNA in Follow-up of Patients With an Advanced Gastroenteropancreatic or Lung Neuroendocrine Tumour Under Everolimus +- SSA Treatment (Liquid-NET 2.0)
NCT05268952 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2022-03-07
Summary
Prospective, multicentric, single arm, POC study to evaluate the value of CtDNA in follow-up of patients treated with everolimus, with or without somatostatin analogues for advanced gastroenteropancreatic or lung neuroendocrine tumours.
Conditions
Interventions
- OTHER
-
Liquid biopsies
Blood/urine sampling and scans are done at regular intervals
- OTHER
-
Scans (CT, gallium-68 DOTATE/TOC/NOC PET-CT)
Scans will be done at regular intervals
Sponsors & Collaborators
-
Universiteit Antwerpen
collaborator OTHER -
University Hospital, Antwerp
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-05-27
- Primary Completion
- 2025-05-27
- Completion
- 2025-12-31
Countries
- Belgium
- Cyprus
Study Locations
More Related Trials
-
Liquid Biopsy (ctDNA) Guided Treatment in Localized Pancreatic Cancer: Neoadjuvant CTX vs. Upfront Surgery
NCT06391892 ·Status: RECRUITING ·Phase: PHASE3
-
Implementing ctDNA and Circular DNA in Patients With Localized Pancreatic Cancer
NCT05788744 ·Status: RECRUITING ·Phase: NA
-
Phase II Study of Pembrolizumab and Lenvatinib in Advanced Well-differentiated Neuroendocrine Tumors
NCT03290079 ·Status: COMPLETED ·Phase: PHASE2
-
Early Treatment ctDNA Dynamics to Predict Response to Chemotherapy
NCT07122466 ·Status: ACTIVE_NOT_RECRUITING
-
A Phase 2 Study of LY2495655 in Participants With Pancreatic Cancer
NCT01505530 ·Status: COMPLETED ·Phase: PHASE2
-
Everolimus and Temozolomide in Advanced Gastroenteropancreatic Neuroendocrine Carcinoma (G3)
NCT02248012 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine, Capecitabine, and Erlotinib in Treating Patients With Advanced Pancreatic Cancer
NCT00885066 ·Status: COMPLETED ·Phase: PHASE1
-
ctDNA Assay in Patients With Resectable Pancreatic Cancer
NCT05052671 ·Status: RECRUITING
-
Using Tumour DNA and Proteins to Better Understand How Pancreatic Cancer Responds to Treatment
NCT06574620 ·Status: RECRUITING ·Phase: NA
-
Erlotinib, Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Cancer
NCT01010945 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Efficacy and Safety of PDR001 in Patients With Advanced or Metastatic, Well-differentiated, Non-functional Neuroendocrine Tumors of Pancreatic, Gastrointestinal (GI), or Thoracic Origin or Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)
NCT02955069 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Study of Combine Modality Therapy in Locally Advanced Pancreatic Cancer
NCT00149578 ·Status: UNKNOWN ·Phase: PHASE2
-
PANCREATIC CANCER: DYNAMIC ASSESSMENT AT ALL STAGES OF TREATMENT
NCT05802485 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk
NCT02478892 ·Status: RECRUITING
-
Safety/Efficacy of Everolimus in Adults With Advanced Pancreatic Neuroendocrine Cancer Not Responsive to Chemotherapy
NCT00363051 ·Status: COMPLETED ·Phase: PHASE2
-
GUIDING MULTI-MODAL THERAPIES AGAINST MINIMAL RESIDUAL DISEASE BY LIQUID BIOPSIES
NCT06102889 ·Status: ENROLLING_BY_INVITATION
-
Multicenter Study of Circulating Tumor DNA in Patients With Pancreatic Cancer Using a Personalized Panel
NCT06043921 ·Status: RECRUITING
-
Early Detection of Pancreatic Cancer
NCT05596435 ·Status: UNKNOWN
-
Biomarker Study in Pancreatic Neuroendocrine Tumours
NCT03130205 ·Status: UNKNOWN
-
Phase IV Study of the Safety and Efficacy of Everolimus in Adult Patients With Progressive pNET in China
NCT02842749 ·Status: COMPLETED ·Phase: PHASE4
-
Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors
NCT05247905 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Bonds Between Circulating Tumoral ADN (ctDNA) and the Development of Peritoneal Carcinomatosis for Patients Under PIPAC
NCT04766502 ·Status: COMPLETED ·Phase: NA
-
Diagnostic Accuracy of Circulating Tumor Cells (CTCs) and Onco-exosome Quantification in the Diagnosis of Pancreatic Cancer - PANC-CTC
NCT03032913 ·Status: COMPLETED
-
INTER-Regional COHORTE of Long Term Pancreatic Cancer Survivors
NCT04436679 ·Status: COMPLETED
-
A Cohort Study on Screening and Follow-up of High-risk Population of PDAC Based on EUS
NCT05621824 ·Status: NOT_YET_RECRUITING