Early Detection of Pancreatic Cancer
NCT05596435 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 496
Last updated 2022-10-27
Summary
The purpose of this study is to enable non-invasive early detection of pancreatic cancer in high-risk populations through the establishment of a machine learning model using plasma cell-free DNA fragmentomics. Plasma cell-free DNA from early stage pancreatic cancer patients and healthy individuals will be subjected to whole-genome sequencing. Features, such as cell-free DNA fragmentation, copy number variations and the status of KRAS gene mutation, will be assessed to generate this model.
Conditions
Interventions
- OTHER
-
No intervention
No intervention
Sponsors & Collaborators
-
Tianjin Medical University Cancer Institute and Hospital
lead OTHER
Principal Investigators
-
Gao Chuntao · Tianjin Medical University Cancer Institute and Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-10-10
- Primary Completion
- 2023-10-12
- Completion
- 2024-10-12
Countries
- China
Study Locations
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