MedTrace Logo

Brain Activity During Bladder Filling: Pilot Study of an fMRI Protocol

NCT05255692 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6

Last updated 2024-06-05

No results posted yet for this study

Summary

Urinary incontinence is the most frequently observed lower urinary tract symptom (LUTS) in children with cerebral palsy (CP) (Samijn et al., 2016).

Higher brain centers responsible for bladder function may be related to the presence of incontinence.

The current pilot study is the first study of a research project focusing on correlations between brain damage and incontinence.

Conditions

  • fMRI Research

Interventions

DIAGNOSTIC_TEST

invasive urodynamic evaluation

Invasive urodynamic evaluation to define maximum cystometric capacity. By means of catheterisation the bladder gets filled and volumes en pressures are measured.

DIAGNOSTIC_TEST

functional magnetic resonance imaging during bladder filling

Functional MRI is used to capture brain activity during tasks. The task in the current study is bladder infusion and withdrawal by means of the INFSYS-2 infusion/withdrawal pump (Leitner et al. 2017)

Sponsors & Collaborators

  • University Ghent

    collaborator OTHER

  • University of Zurich

    collaborator OTHER

  • University Hospital, Ghent

    lead OTHER

Principal Investigators

  • Bieke Samijn, PhD · University Hospital, Ghent

Study Design

Allocation
NA
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-01
Primary Completion
2026-09-30
Completion
2026-09-30

Countries

  • Belgium

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05255692 on ClinicalTrials.gov