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Biomedicines and Bacterial Translocation in Spondyloarthritis

NCT05244109 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2022-06-01

No results posted yet for this study

Summary

The aim of this project is to evaluate the effect of anti-TNF and anti-IL17 biotherapies on bacterial translocation in patients with NSAID-resistant axial spondyloarthritis.

Conditions

  • Axial Spondyloarthritis

Interventions

OTHER

Blood sample

Blood samples (2 times; 21mL per visit)

DRUG

anti-TNF antibody administration

Anti-TNF antibody administration, according to current recommendations and randomization results

DRUG

anti-IL-17 antibody administration

Anti-IL-17 antibody administration, according to current recommendations and randomization results

Sponsors & Collaborators

  • Centre Hospitalier Universitaire de Besancon

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-02-07
Primary Completion
2025-02-28
Completion
2025-05-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05244109 on ClinicalTrials.gov