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Prevalence of the c.853delT Mutation of the HOXB13 Gene in Prostate Cancer in Martinique

NCT05231915 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 465

Last updated 2026-03-31

No results posted yet for this study

Summary

In Martinique, prostate cancer incidence rates are nowadays among the highest worldwide with a high incidence of early-onset and familial forms. We identified a rare heterozygous germline variant c.853delT (p.Ter285Lysfs) rs77179853, reported only among patients of African ancestry with a minor allele frequency of 3.2%. We search to estimate the prevalence of this variant in a sample of prevalent prostate cancer cases managed in urology consultation in Martinique .

Conditions

Interventions

GENETIC

HOXB13 c.853delT mutation

Identify the Allelic frequency of the HOXB13 c.853delT mutation in patients with a cancer prostate in Martinique

Sponsors & Collaborators

  • University Hospital Center of Martinique

    lead OTHER

Study Design

Allocation
NA
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-09
Primary Completion
2024-11-27
Completion
2025-03-09

Countries

  • Martinique

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05231915 on ClinicalTrials.gov