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DNA Sequencing in Clinical Practice, Mayo Clinic Health Tapestry Study

NCT05212428 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 110000

Last updated 2025-12-17

No results posted yet for this study

Summary

This clinical trial collects information on how sequencing a patient's deoxyribonucleic acid (DNA) (i.e., the genetic material) could impact their health care. This study also develops and improves ways to include genomic information from DNA sequencing into the electronic health record to create a more complete "Health Tapestry" for each participant. Sequencing of a patient's DNA leads to the detection of genetic variants some of which determine risk for disease development. Discovery of those genetic variants in a patient could result in prevention, earlier diagnosis or better therapy of disease.

Conditions

  • Genetic Disorder

Interventions

PROCEDURE

Biospecimen Collection

Undergo collection of saliva, blood, urine and stool samples

OTHER

Diagnostic Laboratory Biomarker Analysis

Correlative studies

OTHER

Genetic Counseling

Receive genetic counseling

OTHER

Questionnaire Administration

Complete family history

OTHER

Questionnaire Administration

Ancillary studies

Sponsors & Collaborators

Principal Investigators

  • Konstantinos N. Lazaridis, M.D. · Mayo Clinic in Rochester

Study Design

Allocation
NA
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-22
Primary Completion
2024-11-14
Completion
2026-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05212428 on ClinicalTrials.gov