Adavosertib and Gemcitabine in Advanced Pancreatic
NCT05212025 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2022-06-14
Summary
This study is being done to test the safety and effectiveness of combining Adavosertib and Gemcitabine in patients with pancreatic cancer.
The names of the study drugs involved in this study are:
* Adavosertib
* Gemcitabine
Conditions
Interventions
- DRUG
-
Adavosertib
Taken Orally
- DRUG
-
Intravenous Infusion
Sponsors & Collaborators
- collaborator INDUSTRY
-
Lustgarten Foundation
collaborator OTHER -
Stand Up To Cancer
collaborator OTHER -
James Cleary, MD, PhD
lead OTHER
Principal Investigators
-
James Cleary, MD, PhD · Dana-Farber Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-30
- Primary Completion
- 2023-06-01
- Completion
- 2023-12-31
- FDA Drug
- Yes
More Related Trials
-
Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery
NCT01013649 ·Status: COMPLETED ·Phase: PHASE3
-
Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine Hydrochloride With or Without WEE1 Inhibitor AZD1775 in Treating Patients With Previously Untreated Pancreatic Cancer That Is Metastatic or Cannot Be Removed by Surgery
NCT02194829 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy and Radiation Therapy Plus Surgery in Treating Patients With Advanced Cancer of the Pancreas
NCT00020345 ·Status: COMPLETED ·Phase: PHASE2
-
AS703569 and Gemcitabine Combination in Advanced Malignancies
NCT01097512 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 2, Nab Paclitaxel/Gemcitabine Alone and in Combination With ACP-196 in Subjects With Metastatic Pancreatic Cancer
NCT02570711 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine, Oxaliplatin and Radiotherapy in Treating Patients With Completely Resected Pancreatic Cancer
NCT00191568 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine With or Without Capecitabine in Treating Patients With Advanced Pancreatic Cancer
NCT00030732 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Pancreatic Cancer
NCT00026403 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine With or Without Radiation Therapy in Treating Patients With Pancreatic Cancer
NCT00057876 ·Status: COMPLETED ·Phase: PHASE3
-
High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
NCT01921751 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase II Study of Gemcitabine and Erlotinib As Adjuvant Therapy In Patients With Resected Pancreatic Cancer
NCT00336700 ·Status: TERMINATED ·Phase: PHASE2
-
AZD6244 vs. Capecitabine (Xeloda®) in Patients With Advanced or Metastatic Pancreatic Cancer, Who Have Failed First Line Gemcitabine Therapy
NCT00372944 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Gemcitabine, Nab-paclitaxel, and Ficlatuzumab (AV-299) in Patients With Advanced Pancreatic Cancer
NCT03316599 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas
NCT00003810 ·Status: COMPLETED ·Phase: PHASE2
-
Adenocarcinoma of the Pancreas Treated With Panitumumab and Gemcitabine Regimen to Investigate Overall Survival as Primary Endpoint
NCT00613730 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine Plus Albumin-bound Paclitaxel In Patients With Advanced Metastatic Pancreatic Cancer
NCT00398086 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Gemcitabine With or Without Capecitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
NCT00032175 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy Plus Radiation Therapy With or Without Tipifarnib in Treating Patients With Locally Advanced Pancreatic Cancer
NCT00026104 ·Status: COMPLETED ·Phase: PHASE2
-
Selumetinib and Erlotinib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
NCT01222689 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Gemcitabine Chemoradiation and TNP-470 Patients Locally Advanced, Nonmetastatic Adenocarcinoma of Pancreas
NCT00038701 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine and Celecoxib in Treating Patients With Metastatic Pancreatic Cancer
NCT00068432 ·Status: COMPLETED ·Phase: PHASE2
-
Dovitinib Lactate, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Solid Tumors or Pancreatic Cancer
NCT02048943 ·Status: WITHDRAWN ·Phase: PHASE1
-
Gemcitabine and Nab-paclitaxel Combined With Momelotinib in Participants With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma
NCT02101021 ·Status: TERMINATED ·Phase: PHASE3
-
Erlotinib Combined With Gemcitabine in Treating Patients With Newly Diagnosed Locally Advanced or Metastatic Pancreatic Cancer or Other Solid Tumors
NCT00033241 ·Status: COMPLETED ·Phase: PHASE1
-
AVN944 in Combination With Gemcitabine for the Treatment of Pancreatic Cancer
NCT00493441 ·Status: TERMINATED ·Phase: PHASE2