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Heparinization vs Salinization of the Peripheral Venous Catheter

NCT05209841 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 3450

Last updated 2025-06-25

No results posted yet for this study

Summary

Randomized, double-blind clinical trial to compare the efficacy of catheter sealing with saline, compared to low-dose heparin. 3,450 patients hospitalized at the Hospital Residencia Sant Camil, in Catalonia (Spain), will be randomized to each branch of study. The primary outcome will be the percentage of catheters removed due to obstruction in each branch of study. As secondary outcomes, the number of catheter-associated phlebitis, catheter-associated bacetrihemia, extravasation, and catheter loss will be measured. For the primary outcome, a superiority analysis will be carried out in terms of the percentage of obstructed catheters in each branch of the study.

Conditions

  • Catheter Complications

Interventions

DRUG

Low dose heparin

Catheters will be sealed with 3 mL of Fibrillin Ⓡ (heparin 20UI/mL)

DRUG

Normal saline

Catheters will be sealed with 3mL of 0.9% sodium chloride

Sponsors & Collaborators

  • Consorci Sanitari de l'Alt Penedès i Garraf

    lead OTHER

Principal Investigators

  • Esther Moreno Rubio · CSAPG

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-05
Primary Completion
2026-07-30
Completion
2026-07-30

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05209841 on ClinicalTrials.gov