A Study of STRO-002, an Anti-Folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer
NCT05200364 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 58
Last updated 2025-09-22
Summary
Phase 1 trial to study the safety, pharmacokinetic and Preliminary Efficacy of STRO-002 in combination with Bevacizumab.
Conditions
- Ovarian Cancer
- Ovarian Carcinoma
- Ovary Cancer
- Fallopian Tube Cancer
- Primary Peritoneal Carcinoma
Interventions
- DRUG
-
STRO-002
intravenous antibody drug conjugate
- DRUG
-
anti-VEGF agent
Sponsors & Collaborators
-
Sutro Biopharma, Inc.
lead INDUSTRY
Principal Investigators
-
Arturo Molina, MD · Sutro Biopharma
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-03-22
- Primary Completion
- 2025-06-01
- Completion
- 2025-06-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Bevacizumab in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer
NCT00022659 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate the Safety and Efficacy of TSR-042, Bevacizumab, and Niraparib in Participants With Recurrent Ovarian Cancer
NCT05751629 ·Status: COMPLETED ·Phase: PHASE2
-
Bevacizumab With or Without Everolimus in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
NCT00886691 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer
NCT05920798 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Polyvalent Vaccine-KLH Conjugate + Opt-821 Given in Combination With Bevacizumab
NCT01223235 ·Status: COMPLETED ·Phase: NA
-
Bevacizumab in Treating Patients With Recurrent Sex Cord-Stromal Tumors of the Ovary
NCT00748657 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Niraparib Combined With Bevacizumab Maintenance Treatment in Participants With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy
NCT03326193 ·Status: COMPLETED ·Phase: PHASE2
-
Bevacizumab in Treating Patients With Recurrent or Persistent Endometrial Cancer
NCT00301964 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib and Bevacizumab to Treat Ovarian, Fallopian and Peritoneal Cancer
NCT00436215 ·Status: COMPLETED ·Phase: PHASE2
-
Bevacizumab With or Without Fosbretabulin Tromethamine in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
NCT01305213 ·Status: COMPLETED ·Phase: PHASE2
-
Study of RAD001 and Bevacizumab in Recurrent Ovarian, Peritoneal, and Fallopian Tube Cancer
NCT01031381 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of TRC105 in the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma
NCT01381861 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Bevacizumab Combined With Fluzoparib/Chemotherapy or Fluzoparib in the Treatment of Ovarian Cancer
NCT05170594 ·Status: UNKNOWN ·Phase: PHASE2
-
Bevacizumab With Abraxane in Patients With Recurrent Ovarian/ Peritoneal Cancer
NCT00407563 ·Status: COMPLETED ·Phase: PHASE2
-
Fluzoparib With or Without Bevacizumab for Neoadjuvant Therapy in Advanced Ovarian Cancer
NCT06735326 ·Status: RECRUITING ·Phase: PHASE2
-
Trastzumab Deruxtecan Versus SOC in Recurrent Ovarian That Progressed on Prior PARP Inhibitor Therapy
NCT07340164 ·Status: RECRUITING ·Phase: PHASE2
-
Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy
NCT06083844 ·Status: RECRUITING ·Phase: PHASE2
-
Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer
NCT05231122 ·Status: RECRUITING ·Phase: PHASE2
-
S0025 Irinotecan in Treating Patients With Refractory Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
NCT00053833 ·Status: TERMINATED ·Phase: PHASE2
-
Status of HRD That Lead to a Benefit From Olaparib in Combination With Bevacizumab (STROBE Trial)
NCT06377267 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Gemcitabine/Carboplatin/Bevacizumab to Treat Ovarian, Fallopian Tube or Primary Peritoneal Cancer
NCT00267696 ·Status: COMPLETED ·Phase: PHASE2
-
Bevacizumab and Low-Dose Cyclophosphamide in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal Cancer
NCT00072566 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 1b Study of Paclitaxel And Ricolinostat For The Treatment Of Gynecological Cancer
NCT02661815 ·Status: TERMINATED ·Phase: PHASE1
-
Irinotecan Liposome and Bevacizumab for the Treatment of Platinum Resistant, Recurrent, or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT04753216 ·Status: COMPLETED ·Phase: PHASE2
-
Avastin in Patients With Epithelial Ovarian, Primary Peritoneal Serous or Fallopian Tube Cancer
NCT00866723 ·Status: TERMINATED ·Phase: PHASE2