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Trigeminal Nerve Cardiac Reflex During Resection of Cerebellopontine Angle Tumors and Postoperative Myocardial Injury

NCT05198648 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 476

Last updated 2025-02-14

No results posted yet for this study

Summary

Myocardial injury after noncardiac surgery is significantly related to postoperative 30-day mortality. Trigeminal cardiac reflex is one of the main causes of perioperative cardiac emergency. Therefore, the investigators' aim is to test the hypothesis that trigeminal cardiac reflex associates postoperative myocardial damage in participants undergoing skull base tumor surgery. The investigators will observe the association between trigeminal cardiac reflex and myocardial injury by measuring the concentration of plasma high sensitivity cardiac troponin (hs-cTnT) in participants after skull base tumor surgery.

Conditions

  • Myocardial Injury
  • Trigeminal Cardiac Reflex

Interventions

OTHER

Trigeminal cardiac reflex

Trigeminal cardiac reflex occurred during the cerebellopontine angle tumor surgery.

OTHER

Non-trigeminal cardiac reflex

No trigeminal cardiac reflex occurred during the cerebellopontine angle tumor surgery.

Sponsors & Collaborators

  • Beijing Tiantan Hospital

    lead OTHER

Principal Investigators

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-07-01
Primary Completion
2024-10-01
Completion
2024-10-09

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05198648 on ClinicalTrials.gov