Treatment of Allergic Rhinitis and Chronic Polypous Rhinosinusitis With Olfactory Mucosa-derived Mesenchymal Stem Cells
NCT05167552 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2022-01-19
Summary
Treatment of patients with allergic rhinitis and chronic polypous rhinosinusitis with olfactory mucosa-derived mesenchymal stem cells
Conditions
- Allergic Rhinitis
- Rhinosinusitis Chronic
Interventions
- BIOLOGICAL
-
Olfactory mucosa-derived mesenchymal stem cells
Olfactory mucosa-derived mesenchymal stem cells
- OTHER
-
Standard treatment of type Allergic Rhinitis according to the clinical protocols
Standard treatment of type Allergic Rhinitis according to the clinical protocols
- OTHER
-
Standard treatment of type Chronic Polypous Rhinosinusitis according to the clinical protocols
Standard treatment of type Chronic Polypous Rhinosinusitis according to the clinical protocols
Sponsors & Collaborators
-
The Republican Center for Research and Practice in Otolaryngology
collaborator UNKNOWN -
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
lead OTHER_GOV
Principal Investigators
-
Natalia Antonevich, Dr · the Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
-
Yulia Eremenko, Prof · The Republican Center for Research and Practice in Otolaryngology
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-03-01
- Primary Completion
- 2023-12-31
- Completion
- 2023-12-31
More Related Trials
-
S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps
NCT02291549 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of RhinAer Stylus for Treating Chronic Rhinitis
NCT06599736 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Oxymetazoline Hydrochloride in Combination With Nasal Glucocorticosteroid for Perennial Allergic and Non-allergic Rhinitis in Subjects With Persistent Nasal Congestion
NCT00584662 ·Status: TERMINATED ·Phase: NA
-
Nasal Microbiota Transfer Therapy in Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
NCT05400616 ·Status: RECRUITING ·Phase: NA
-
Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps
NCT06129552 ·Status: RECRUITING
-
Establishment of Precise Diagnosis and Treatment System for Refractory Chronic Rhinosinusitis
NCT05390255 ·Status: UNKNOWN ·Phase: PHASE3
-
The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus Surgery
NCT02562924 ·Status: COMPLETED ·Phase: NA
-
Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis
NCT02784262 ·Status: COMPLETED ·Phase: PHASE2
-
A Randomized Double Dummy Double Blind Dose Determining Place-bo Controlled Study to Evaluate Efficacy of Investigational Product E-RH-06 at 2 Dose Levels for the Metabolic Management of Chronic or Recurrent, Non-infective Nasal Congestion With-or-without Rhinorrhea.
NCT01546662 ·Status: UNKNOWN ·Phase: NA
-
NasoNeb Delivery of an Intranasal Steroid
NCT01270256 ·Status: COMPLETED ·Phase: PHASE4
-
Study Evaluating the Efficacy and Safety of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi Directional Device in Subjects With Bilateral Nasal Polyposis Followed by an 8-Week Open-Label Extension Phase to Assess Safety
NCT01622569 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety Study of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Using a Novel Bi-directional Device
NCT01624662 ·Status: COMPLETED ·Phase: PHASE3
-
Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma
NCT06069310 ·Status: ACTIVE_NOT_RECRUITING
-
A Clinical Evaluation of a Steroid-Coated Sinus Stent When Used Following Functional Endoscopic Sinus Surgery in Patients With Chronic Sinusitis
NCT01253577 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Two Steroid Nasal Implants Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis
NCT03729310 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
The Study of GR1802 in Patients with Chronic Rhinosinusitis with Nasal Polyps
NCT05873803 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Chronic Rhinosinusitis Symptoms in Asthma Patients Undergoing Treatment With Reslizumab
NCT03369574 ·Status: WITHDRAWN
-
Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study
NCT01255566 ·Status: COMPLETED
-
Safety and Performance of the Steroid-Releasing S8 Sinus Implant
NCT01894503 ·Status: COMPLETED ·Phase: PHASE2
-
Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis
NCT01066104 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of MSCs Derived Pleiotropic Factors on Wound Healing in Endonasal Surgeries
NCT04536233 ·Status: UNKNOWN ·Phase: PHASE1
-
Efficacy and Safety of Budesonide Inhalation Suspension for the Treatment of Chronic Rhinosinusitis With Polyposis.
NCT03687515 ·Status: COMPLETED ·Phase: PHASE3
-
The Study of Long-term Outcomes of GR1802 in Patients With Chronic Rhinosinusitis With Nasal Polyps
NCT06015243 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy of ArchSinus, NasoPore & Propel to Prevent Post-Surgical MT Lateralization and Improve Symptomatic Outcomes
NCT05156801 ·Status: UNKNOWN ·Phase: NA
-
Effects of Radiofrequency Ablation of Posterior Nasal Nerves on Inflammatory Cytokines, Peak Nasal Inspiratory Flow, and Nasal Blood Flow in Patients With Chronic Rhinitis
NCT05648565 ·Status: COMPLETED ·Phase: NA