Microsatellite Instability in Colorectal Cancers
NCT05162248 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 231
Last updated 2021-12-17
Summary
In this study, we aimed to identify the different histopathological features of tumors with microsatellite instability (MSI) compared to microsatellite stable (MSS) in patients who underwent surgery for colorectal cancer. We also planned to determine how MSI affects prognostic parameters.
Conditions
- Colorectal Cancer
- Colorectal Carcinoma
- Microsatellite Instability High
- Microsatellite Instability Low
- Microsatellite Instability-High
Interventions
- DIAGNOSTIC_TEST
-
Microsatellite instability analysis
Molecular analysis for Microsatellite Instability (MSI) status was performed using immunohistochemistry (IHC). IHC now recognized as an approved method to highly precision predict MSI in colorectal cancer.
Sponsors & Collaborators
-
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
lead OTHER
Principal Investigators
-
Taygun Gülşen, MD · Sultan 2. Abdulhamid Training and Research Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-04-01
- Primary Completion
- 2021-07-15
- Completion
- 2021-08-01
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Prognosis Stratification for pT4bN0M0 Colorectal Cancer Following Multivisceral Resection
NCT06115837 ·Status: COMPLETED
-
mFOLFOX6+Bevacizumab+PD-1 Monoclonal Antibody in Local Advanced MSS CRC
NCT04895137 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating Factors Affecting Survival in Colon and Rectum Cancer
NCT05388513 ·Status: COMPLETED
-
Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer
NCT07154316 ·Status: RECRUITING ·Phase: PHASE2
-
The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer
NCT06540027 ·Status: ENROLLING_BY_INVITATION
-
Comparison of Expression of Carcinogenesis-related Molecular Markers in the Patients With Colon Cancer and Polyp
NCT05638542 ·Status: ACTIVE_NOT_RECRUITING
-
The Status of Immune Checkpoints at Gastrointestinal Cancer
NCT04566848 ·Status: COMPLETED
-
Short Course Radiotherapy, Unresectable Rectal Cancer, Liver Metastasis
NCT03022734 ·Status: UNKNOWN ·Phase: PHASE2
-
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
NCT03659448 ·Status: RECRUITING ·Phase: PHASE3
-
Maintenance Tislelizumab + Capecitabine to Treat Metastatic Colorectal Cancer
NCT05360277 ·Status: RECRUITING ·Phase: PHASE2
-
Immune Checkpoints in Predicting Response to Neoadjuvant Therapy in Rectal Cancer
NCT05457075 ·Status: COMPLETED
-
Efficacy of Combination Immunotherapy in Patients With Metastatic Colorectal Cancer
NCT05414461 ·Status: COMPLETED ·Phase: PHASE2
-
The Impact of Immune Cell Changes During the Perioperative Period on the Prognosis of Patients With Colorectal Cancer
NCT05015296 ·Status: UNKNOWN
-
Maintenance Treatment With Capecitabine in Colorectal Cancer Patients
NCT02027363 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of Biomarkers in Tissue Samples From Patients With Metastatic Colon Cancer
NCT01012804 ·Status: WITHDRAWN
-
Multicenter Retrospective Study on Optimizing Combination Immunotherapy Strategies in MSS/MSI-L/pMMR Advanced Colorectal Cancer
NCT06849362 ·Status: ENROLLING_BY_INVITATION
-
The CSTME Associates With the Prognosis of Stage II and III Colorectal Cancer
NCT05420415 ·Status: COMPLETED
-
Recent Trends in Stage Migration of Gastrointestnial Carcinoid Tumors Over Two Decades: a Retrospective SEER-based Analysis 2000-2022
NCT07317726 ·Status: COMPLETED
-
AREG, EREG and EGFR: Response to Anti-EGFR Agents in Colorectal Cancer
NCT03986541 ·Status: COMPLETED
-
Different Cycles of Preoperative Neoadjuvant Sintilimab in Mismatch-repair Deficient/microsatellite Instability-high, Locally Advanced Colorectal Cancer
NCT06698757 ·Status: RECRUITING ·Phase: PHASE2
-
Exploration of the Relationship Between Mismatch Repair Status of Colorectal Cancer and Lymph Node Metastasis Patterns and Pathological High-risk Factors
NCT06798857 ·Status: COMPLETED
-
Detection of CTCs in Stage III Rectal Cancer Patients Undergoing Neoadjuvant Therapy
NCT02554448 ·Status: UNKNOWN ·Phase: NA
-
Significance of Cortactin Expression in Colorectal Adenocarcinomas
NCT05225870 ·Status: COMPLETED ·Phase: NA
-
The Continuing Care Needs in Colorectal Cancer Patients in Different Stages
NCT00961129 ·Status: UNKNOWN
-
A Real-world Study of Chidamide in Combination with PD-1/PD-L1 Antibodies and Anti-angiogenic Agents in Advanced MSS Colorectal Cancer
NCT06682247 ·Status: NOT_YET_RECRUITING