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Corticospinal and Motor Behavior Responses After Physical Therapy Intervention in Patients With Chronic Low Back Pain.

NCT05156242 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 96

Last updated 2025-05-09

No results posted yet for this study

Summary

This study aims to 1) determine the immediate effects of transcranial direct current stimulation (tDCS) on corticospinal excitability, lumbar multifidus muscle (LM) activation, as well as lumbar stability in patients with chronic low back pain (CLBP), 2) determine the immediate effects of neuromuscular electrical stimulation (NMES) on corticospinal excitability, LM activation, as well as lumbar stability in patients with CLBP, 3) compare the effectiveness of 6-week intervention program among tDCS priming with motor control exercise (MCE), NMES priming with MCE, and MCE alone in patients with CLBP, and 4) determine the associations among corticospinal excitability, LM activation, lumbar stability, movement patterns, and clinical outcomes in patients with CLBP.

Conditions

  • Low Back Pain

Interventions

DEVICE

Active-tDCS priming MCE

tDCS is used to enhance cortical excitability before motor control exercises.

DEVICE

Sham-tDCS priming MCE

tDCS will be set at 0 mA for 20 minutes before motor control exercise.

DEVICE

NMES priming MCE

NMES is used to enhance lumbar multifidus motor unit recruitment before motor control exercise.

OTHER

Conventional physical therapy

Conventional physical therapy includes modality for pain control, general exercise to improve muscle strength, endurance, and flexibility, and functional training (sit to stand, walking, etc.).

Sponsors & Collaborators

  • University of South Carolina

    collaborator OTHER

  • Mahidol University

    lead OTHER

Principal Investigators

  • Peemongkon Wattananon · Mahidol University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-03
Primary Completion
2024-10-31
Completion
2024-12-31

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05156242 on ClinicalTrials.gov