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Acute Mechanisms of Cervical Transcutaneous Electrical Stimulation of the Spinal Cord

NCT04843137 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2023-10-30

No results posted yet for this study

Summary

The purpose of this study is to examine how delivery of subthreshold electrical stimulation of the spinal cord alters the excitability of neural pathways and consequently movement performance in healthy and spinal cord injured individuals. Specifically, we assess how stimulation parameters such as electrode configurations and stimulation frequency affect spinal excitability, corticospinal excitability, intracortical excitability, motor unit properties and force production. This study is not an intervention study, but a mechanistic study trying to shed light on how this novel neuromodulatory technique acutely affects the central nervous system.

Conditions

  • Spinal Cord Injuries

Interventions

DEVICE

Cervical Transcutaneous Electrical Spinal Cord Stimulation

Surface electrodes are placed over the cervical spinal cord. Constant current is delivery through these electrodes. Stimulation frequency and electrode configuration are manipulated, and outcome measures are recorded.

Sponsors & Collaborators

  • University of Louisville

    lead OTHER

Principal Investigators

  • Jessica D'Amico, PhD · University of Louisville

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-04-06
Primary Completion
2022-02-22
Completion
2022-02-22
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04843137 on ClinicalTrials.gov