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Comprehensive Diagnosis and Treatment Strategy for Opportunistic Fungal Infections in AIDS Patients

NCT05153005 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 600

Last updated 2021-12-13

No results posted yet for this study

Summary

Opportunistic fungal infection is the most common opportunistic infection in AIDS patients, with the high mortality and recurrence rate due to the lack of standardized comprehensive diagnosis and treatment strategy. This project aims to combine traditional detection and observation indicators with molecular biology, serology and mass spectrometry identification technology to develop early screening and diagnostic strategies for opportunistic fungal infections in AIDS patients, explore scientific evaluation methods for anti-fungal efficacy and formulate comprehensive strategies for reducing the mortality and recurrence rate.

Conditions

  • Opportunistic Fungal Infections

Interventions

OTHER

examination methods

Some advanced methods: mannose protein (Mp1p), (1,3)- β- D-glucan (G antigen) and Cryptococcus capsular antigen (CrAg) serological detection, qPCR, dd- PCR and mass spectrometry identification, QFC.

Sponsors & Collaborators

  • Guangzhou 8th People's Hospital

    lead OTHER

Principal Investigators

  • Ruosu Ying, PhD · Guangzhou Eighth People's Hospital, Guangzhou Medical University

Eligibility

Min Age
16 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-01
Primary Completion
2022-12-31
Completion
2023-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05153005 on ClinicalTrials.gov