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Effects of a Marine Protein Hydrolysate in Healthy Adults

NCT05149079 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 67

Last updated 2021-12-08

No results posted yet for this study

Summary

This randomized, double blind, controlled trial investigates changes in the cardiovascular index (triacylglycerol/HDL-cholesterol × waist/hip ratio) after 12 weeks of marine protein hydrolysate (MPH) or whey protein powder (placebo) supplementation in adult healthy persons. Additionally, the study investigates potential effects on plasma parameters of metabolic health including lipids, glucose, inflammatory parameters and redox state, as well as associations between dietary MPH and body weight, abdominal obesity, body composition, and gut microbiota composition. Finally, putative end-products of diet-microbial interactions (TMAO and short-chain fatty acids) with CVD risk factors and biomarkers of mitochondrial function are examined.

Conditions

  • Healthy Diet

Interventions

DIETARY_SUPPLEMENT

Cod protein hydrolysate

Rest raw materials (RRM) from cod (Fjordlaks AS, Norway) are used for the hydrolysis production (Food Grade). Freshly minced RRM is treated wth enzymes optimized to generate bioactive hydrolysates using facilities and techniques approved for human consumption.

DIETARY_SUPPLEMENT

Placebo

Whey protein powder, commercially available

Sponsors & Collaborators

  • Haukeland University Hospital

    collaborator OTHER

  • Alesund Hospital

    collaborator OTHER

  • Norwegian University of Science and Technology

    collaborator OTHER

  • University of Bergen

    lead OTHER

Principal Investigators

  • Rolf K Berge, PhD · University of Bergen, Norway

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-02-01
Primary Completion
2021-05-15
Completion
2021-05-31

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05149079 on ClinicalTrials.gov