Interactions Between Antihypertensive Drugs and Drugs Prescribed in the Emergency Room
NCT05140590 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 53
Last updated 2022-03-29
Summary
Drug interactions (IFF) are events that occur when multiple drugs are administered at the same time to an individual. People with arterial hypertension generally require therapeutic regimens based on 2 or more drugs for their adequate control, which makes them patients with polypharmacy. When these patients require urgent medical attention, there is a risk that IFFs will occur between their base treatment and the drugs that are prescribed to solve the added condition.
Objective. To determine the frequency of pharmacological interactions between antihypertensive regimens and drugs used in the emergency service of Hospital General de Zona No 51 (HGZ 51).
Material and methods: Observational, descriptive, and prospective study. The participants will be eligible patients with systemic arterial hypertension treated in the emergency room of HGZ 51 in Gómez Palacio, Durango. Support systems will be used for clinical decision, to identify potential IFFs and to be able to classify them according to their mechanism (pharmacokinetics and pharmacodynamics) and severity. A descriptive statistical analysis will be carried out in the SPSS program using measures of frequency, dispersion and central tendency.
Conditions
- Drug Interactions
- Hypertension
Sponsors & Collaborators
-
Instituto Mexicano del Seguro Social
lead OTHER_GOV
Principal Investigators
-
Lilia E Luque-Esparza, Dra. · IMSS
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-01-01
- Primary Completion
- 2021-12-31
- Completion
- 2022-02-28
Countries
- Mexico
Study Locations
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