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REMASTer: REcurrent Brain Metastases After SRS Trial

NCT05124912 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 261

Last updated 2026-02-20

No results posted yet for this study

Summary

Randomized, post-market multi-center study investigating the efficacy of two sets of treatment algorithms in brain metastases (BM) patients at the time of first intervention for radiographic progression after stereotactic radiosurgery (SRS), with or without surgery.

Conditions

Interventions

PROCEDURE

Radiation Therapy

Post-op hypofractionated therapy or no radiation therapy

DRUG

Steroid Therapy

Best medical management with steroid therapy

PROCEDURE

Laser Interstitial Thermal Therapy

Minimally invasive technique to necrotize intracranial lesions using the NeuroBlate® System (NBS)

Sponsors & Collaborators

  • Monteris Medical

    lead INDUSTRY

Principal Investigators

  • Peter Fecci, MD · University of Colorado, Denver

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-10
Primary Completion
2026-12-31
Completion
2028-10-31
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05124912 on ClinicalTrials.gov